Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775886 | 0.88 | TBXAS1 (0.68) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL8775878 | 0.86 | TBXAS1 (0.71) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL8775940 | 0.86 | TBXAS1 (0.71) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL8775786 | 0.86 | TBXAS1 (0.71) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL9312882 | 0.85 | TBXAS1 (0.50) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL9311629 | 0.85 | TBXAS1 (0.47) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL9874670 | 0.82 | SLC6A2 (0.57) | TBXAS1SLC6A2SLC6A4SLC6A3EPHX2 | |
| SCHEMBL8775789 | 0.82 | SMN1; SMN2 (0.58) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL128570 | 0.82 | HRH1 (0.56) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL23970158 | 0.81 | TBXAS1 (0.56) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |