Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710717 | 0.88 | LMNA (0.39) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL1710596 | 0.86 | LMNA (0.37) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL20491528 | 0.86 | LMNA (0.37) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL2208804 | 0.86 | LMNA (0.37) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL2206227 | 0.86 | LMNA (0.37) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL121125 | 0.84 | LMNA (0.39) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL7705221 | 0.80 | USP2 (0.42) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL14414058 | 0.80 | USP2 (0.42) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL1062380 | 0.80 | — | — | |
| SCHEMBL2907078 | 0.76 | KDM4E (0.32) | ALDH1A1LMNAKDM4EUSP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570263-B1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR (FR) | 1997-12-03 | — | — | EP | disclosed |
| EP-0570263-A1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-11-18 | — | — | EP | disclosed |