Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.64 |
| ▸ | RARA | P10276 | 5/20 | 0.64 |
| ▸ | RARG | P13631 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | GOT1 | P17174 | 1/20 | 0.64 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641031 | 0.92 | RARB (0.67) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL566075 | 0.87 | HDAC11 (0.62) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL14027627 | 0.85 | RARB (0.82) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL5827566 | 0.83 | HDAC11 (0.68) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL9078617 | 0.82 | RARA (0.64) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL5827886 | 0.82 | RARB (0.70) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL25200687 | 0.81 | RARB (0.69) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL13550931 | 0.81 | RARB (0.69) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL29869357 | 0.81 | RARB (0.69) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL10046790 | 0.81 | RARB (0.59) | RARBRARARARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |