Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520719 | 0.86 | MEN1 (0.50) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL429910 | 0.85 | MAOA (0.58) | NPC1RAB9ATDP1MEN1KMT2A | |
| SCHEMBL29549500 | 0.85 | MAOA (0.58) | NPC1RAB9ATDP1MEN1KMT2A | |
| Styrene SCHEMBL28042731 | 0.82 | ALDH1A1 (0.56) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL28609933 | 0.82 | LCK (0.60) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL2321099 | 0.82 | NPC1 (0.49) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL31583125 | 0.81 | LCK (0.51) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL26208667 | 0.81 | NPC1 (0.43) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL410570 | 0.81 | KDM4E (0.57) | NPC1RAB9ATP53TDP1MAPT | |
| SCHEMBL27962457 | 0.81 | TDP1 (0.44) | NPC1RAB9ATP53TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529583-B1 | 3-(Vinylphenyloxy) propylsilane compound | SHINETSU CHEMICAL CO (JP) | 1997-11-26 | — | — | EP | disclosed |
| US-5210252-A | 3-(VINYLPHENYLOXY)PROPYLSILANE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0529583-A1 | 3-(Vinylphenyloxy) propylsilane compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |