SCHEMBL8776584

SCHEMBL8776584

C=CC(=O)OCC1(CC)COC(=O)OC1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.38
HPGD P15428 1/20 0.38
PRKCA P17252 2/20 0.36
ATM Q13315 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384901 0.84 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14067773 0.82 PRKCA (0.40) TSHRPRKCAATMALDH1A1
SCHEMBL12904846 0.81 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL275851 0.81 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13968333 0.81 TSHR (0.37) TSHRHPGDATMALDH1A1TP53
SCHEMBL10581736 0.81 PRKCA (0.39) TSHRPRKCAATM
SCHEMBL24702089 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8393354 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9507214 0.80 PRKCA (0.35) TSHRPRKCAATM
SCHEMBL8554482 0.79 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022325-A1 COMPOSITION MADE FROM (METH)ACRYLATE MONOMERS BOSTIK SA (FR) 2023-01-26 US disclosed
US-8778575-B2 Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
US-8778575-B2 Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
US-20100291116-A1 MICROPARTICLE COMPRISING CROSS-LINKED POLYMER DSM IP ASSETS B.V. (NL) 2010-11-18 US disclosed
US-20100291116-A1 MICROPARTICLE COMPRISING CROSS-LINKED POLYMER DSM IP ASSETS B.V. (NL) 2010-11-18 US disclosed
US-20090011367-A1 INTERFACE BINDER, RESIST COMPOSITION CONTAINING THE SAME, LAMINATE FOR FORMING MAGNETIC RECORDING MEDIUM HAVING LAYER CONTAINING THE SAME, MANUFACTURING METHOD OF MAGNETIC RECORDING MEDIUM USING THE SAME, AND MAGNETIC RECORDING MEDIUM PRODUCED BY THE MANUFACTURING METHOD FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-20090011367-A1 INTERFACE BINDER, RESIST COMPOSITION CONTAINING THE SAME, LAMINATE FOR FORMING MAGNETIC RECORDING MEDIUM HAVING LAYER CONTAINING THE SAME, MANUFACTURING METHOD OF MAGNETIC RECORDING MEDIUM USING THE SAME, AND MAGNETIC RECORDING MEDIUM PRODUCED BY THE MANUFACTURING METHOD FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
EP-0687667-B1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO LTD (JP) 1997-12-03 EP disclosed
US-5534647-A Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO., LTD. (JP) 1996-07-09 US disclosed
EP-0687667-A1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO., LTD. (JP) 1995-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291116-A1 MICROPARTICLE COMPRISING CROSS-LINKED POLYMER CBR3, CBR1, CNR2 TSHR 960/4885HPGD 1296/4885PRKCA 3347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.