Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MYOC | Q99972 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573967 | 0.94 | MAPT (0.66) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL2082944 | 0.87 | KMT2A (0.58) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14601827 | 0.87 | MAPT (0.57) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL95959 | 0.87 | KMT2A (0.57) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4963324 | 0.87 | MAPT (0.57) | MAPTKMT2AMEN1NPC1RAB9A | |
| 4-Nitrophenyl Phenylcarbamate SCHEMBL1434931 | 0.86 | ALDH1A1 (0.62) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6261538 | 0.86 | MAPT (0.62) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL25490115 | 0.84 | MEN1 (0.56) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL18779728 | 0.84 | MAPT (0.55) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL31522080 | 0.84 | MEN1 (0.67) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799202-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |