SCHEMBL95959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3573967	0.92	MAPT (0.66)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL8776629	0.87	MAPT (0.59)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL14601827	0.85	MAPT (0.57)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL2082944	0.85	KMT2A (0.58)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL4963324	0.85	MAPT (0.57)	KMT2AMAPTMEN1NPC1RAB9A
	4-Nitrophenyl Phenylcarbamate SCHEMBL1434931	0.85	ALDH1A1 (0.62)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL6261538	0.85	MAPT (0.62)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL31188395	0.83	KMT2A (0.57)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL25490115	0.83	MEN1 (0.56)	KMT2AMAPTMEN1NPC1RAB9A
	SCHEMBL18779728	0.83	MAPT (0.55)	KMT2AMAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.