Nitrogen

Nitrogen

SCHEMBL8776690

COc1ccc(OC)c(N2CCOCC2)c1.N#N

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
HSD17B10 Q99714 1/20 0.60
LMNA P02545 1/20 0.55
ALDH1A1 P00352 7/20 0.54
KDM4E B2RXH2 5/20 0.54
PRKDC P78527 3/20 0.52
HTT P42858 2/20 0.50
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CLK1 P49759 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HPGD P15428 2/20 0.46
GAA P10253 2/20 0.46
TSHR P16473 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPC1 O15118 1/20 0.46
GLA P06280 1/20 0.46
RAB9A P51151 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL11214740 0.98 MAPT (0.58) MAPTHSD17B10LMNAALDH1A1KDM4E
SCHEMBL30861221 0.97 MAPT (0.62) MAPTHSD17B10LMNAALDH1A1KDM4E
SCHEMBL26472755 0.97 MAPT (0.62) MAPTHSD17B10LMNAALDH1A1KDM4E
Nitrogen SCHEMBL11687589 0.90 MAPT (0.54) MAPTHSD17B10LMNAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL11224564 0.87 MAPT (0.54) MAPTHSD17B10LMNAALDH1A1KDM4E
SCHEMBL8382286 0.85 MAPT (0.67) MAPTHSD17B10LMNAALDH1A1KDM4E
SCHEMBL9830402 0.82 MAPT (0.63) MAPTHSD17B10LMNAALDH1A1KDM4E
SCHEMBL10035043 0.81 PRKDC (0.55) MAPTHSD17B10ALDH1A1KDM4EPRKDC
SCHEMBL12046912 0.81 ALDH1A1 (0.50) MAPTHSD17B10ALDH1A1PRKDCHTT
SCHEMBL8321228 0.79 AKR1C3 (0.49) MAPTHSD17B10LMNAALDH1A1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490515-B1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
US-5480762-A Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed
EP-0490515-A1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-06-17 EP disclosed
US-4701399-A Photosensitive composition with 2-halomethyl-5-substituted-1,3,4-oxadiazole FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed
US-4614701-A COLOR FILTERS, FOR TELEVISION AND LIQUID CRYSTAL DISPLAYS SEKISUI FINE CHEMICAL CO., LTD. (JP) 1986-09-30 US disclosed
US-4500617-A ALUMINUM (OR ALLOY) SUPPORT, HYDROPHILIC ALUMINUM OXIDE, PHOTOSENSITIVE AND PHOTOCONDUCTIVE INSULATION LAYER FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
US-4399210-A O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT FUJI PHOTO FILM COMPANY LTD. (JP) 1983-08-16 US disclosed
US-4279982-A PRINTOUTS; OXADIAZOLE PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-07-21 US disclosed
US-4232106-A Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed