Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382286 | 0.92 | MAPT (0.67) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5566877 | 0.85 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2204461 | 0.84 | MAPT (0.58) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2349863 | 0.84 | HTR3A (0.69) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL26472755 | 0.84 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30861221 | 0.84 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13030868 | 0.84 | ALDH1A1 (0.59) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7486606 | 0.83 | MAPT (0.56) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7708526 | 0.83 | HTR3A (0.68) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| Nitrogen SCHEMBL8776690 | 0.82 | MAPT (0.60) | MAPTLMNAALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| US-11320376-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP MDX LLC (US) | 2022-05-03 | — | — | US | disclosed |
| EP-3668884-B1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP INC (US) | 2022-03-09 | — | — | EP | disclosed |
| US-20210041360-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2021-02-11 | — | — | US | disclosed |
| US-10890529-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| EP-3668884-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITechGroup Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| US-10677728-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP B.V. (NL) | 2020-06-09 | — | — | US | disclosed |
| US-20200173924-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2019036225-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10677728-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885LMNA 1428/4885ALDH1A1 1848/4885 |
| US-20200173924-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DDB1, DUT, DCLRE1B | MAPT 4249/4885LMNA 1428/4885ALDH1A1 1848/4885 |
| US-10890529-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885LMNA 1428/4885ALDH1A1 1848/4885 |
| US-11320376-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885LMNA 1428/4885ALDH1A1 1848/4885 |
| US-20210041360-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DDB1, DUT, DCLRE1B | MAPT 4249/4885LMNA 1428/4885ALDH1A1 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.