SCHEMBL8776803

SCHEMBL8776803

NSc1c[c]ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8155628 0.79 MAOA (0.34)
SCHEMBL10716988 0.77
SCHEMBL2306127 0.75
SCHEMBL1287329 0.75
SCHEMBL97740 0.75
SCHEMBL5652848 0.75
SCHEMBL919863 0.73 MAOA (0.45)
SCHEMBL28235092 0.71
SCHEMBL6860279 0.71
SCHEMBL11661367 0.70 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810435-A2 Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1997-12-03 EP disclosed
US-5175269-A Labeled diagnostic and therapeutic agents ENZO DIAGNOSTICS, INC. (US) 1992-12-29 US disclosed
US-5013831-A Medical diagnosis, therapy ENZO BIOCHEM, INC. (US) 1991-05-07 US disclosed
US-5002885-A Detectable molecules, method preparation and use ENZO BIOCHEM, INC. (US) 1991-03-26 US disclosed
US-4952685-A CARRYING A METAL COMPLEXING OR BIOTIN DETECTABLE GROUPS; NUCLEOTIDES ENZO BIOCHEM, INC. (US) 1990-08-28 US disclosed
US-4943523-A METAL CHELATING GROUPS OR BIOTIN ATTACHED TO POLYSACCHARIDES, POLYPEPTIDES, POLYNUCLEOTIDES OR SYNTHETIC POLYMERS; IMMUNOASSAY IMAGING ENZO BIOCHEM, INC. (US) 1990-07-24 US disclosed
US-4849208-A Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1989-07-18 US disclosed
US-4849505-A Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1989-07-18 US disclosed
US-4843122-A COUPLING AGENT BETWEEN BIOPOLYMER AND CHELATE AGENT OR BIOTIN ENZO BIOCHEM, INC. (US) 1989-06-27 US disclosed
US-4707440-A BIOPOLYMER LINKED TO A CHELATING AGENT BASED ON AN O-CYCLOHEXADIAMINEDIACETIC ACID ENZO BIOCHEM, INC. (US) 1987-11-17 US disclosed
EP-0154788-A2 Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1985-09-18 EP disclosed