SCHEMBL8776834

SCHEMBL8776834

[CH2]CC1CCC(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PLG P00747 1/20 0.40
▸ PLAT P00750 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ GABRR1 P24046 5/20 0.37
▸ GABRR2 P28476 1/20 0.37
▸ PEPD P12955 1/20 0.36
▸ SLC1A2 P43004 2/20 0.33
▸ SLC1A1 P43005 2/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ GRM3 Q14832 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958476 0.81 LMNA (0.43) PLGPLATLMNAGABRR1GABRR2
SCHEMBL14972605 0.81 PLG (0.43) PLGPLATLMNAGABRR1GABRR2
SCHEMBL2816981 0.77 PLG (0.40) PLGPLATLMNAGABRR1GABRR2
SCHEMBL9173498 0.77 PLG (0.36) PLGPLATLMNAGABRR1GABRR2
SCHEMBL29282898 0.76 PLG (0.39) PLGPLATLMNAGABRR1GABRR2
SCHEMBL30922239 0.76 PLG (0.39) PLGPLATLMNAGABRR1GABRR2
SCHEMBL14972575 0.76 PEPD (0.39) PLGPLATLMNAGABRR1GABRR2
SCHEMBL29282870 0.76 PLG (0.39) PLGPLATLMNAGABRR1GABRR2
SCHEMBL29282868 0.76 PLG (0.39) PLGPLATLMNAGABRR1GABRR2
SCHEMBL16349314 0.74 GABRR1 (0.53) LMNAGABRR1GABRR2PEPDSLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810435-A2 Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1997-12-03 — — EP disclosed
US-5175269-A Labeled diagnostic and therapeutic agents ENZO DIAGNOSTICS, INC. (US) 1992-12-29 — — US disclosed
US-5013831-A Medical diagnosis, therapy ENZO BIOCHEM, INC. (US) 1991-05-07 — — US disclosed
US-5002885-A Detectable molecules, method preparation and use ENZO BIOCHEM, INC. (US) 1991-03-26 — — US disclosed
US-4952685-A CARRYING A METAL COMPLEXING OR BIOTIN DETECTABLE GROUPS; NUCLEOTIDES ENZO BIOCHEM, INC. (US) 1990-08-28 — — US disclosed
US-4943523-A METAL CHELATING GROUPS OR BIOTIN ATTACHED TO POLYSACCHARIDES, POLYPEPTIDES, POLYNUCLEOTIDES OR SYNTHETIC POLYMERS; IMMUNOASSAY IMAGING ENZO BIOCHEM, INC. (US) 1990-07-24 — — US disclosed
US-4849208-A Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1989-07-18 — — US disclosed
US-4849505-A Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1989-07-18 — — US disclosed
US-4843122-A COUPLING AGENT BETWEEN BIOPOLYMER AND CHELATE AGENT OR BIOTIN ENZO BIOCHEM, INC. (US) 1989-06-27 — — US disclosed
US-4707440-A BIOPOLYMER LINKED TO A CHELATING AGENT BASED ON AN O-CYCLOHEXADIAMINEDIACETIC ACID ENZO BIOCHEM, INC. (US) 1987-11-17 — — US disclosed
EP-0154788-A2 Detectable molecules, method of preparation and use ENZO BIOCHEM, INC. (US) 1985-09-18 — — EP disclosed
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