Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777005 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019755 | 0.79 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8210030 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777006 | 0.75 | KDM4E (0.35) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9422338 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777015 | 0.73 | PDE3A (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8205815 | 0.72 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8210725 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9845278 | 0.71 | SYK (0.31) | — | |
| SCHEMBL9019861 | 0.70 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693071-B1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0693071-A1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024134-A1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-27 | — | — | WO | disclosed |