Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777001 | 0.95 | PDE3A (0.40) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8210725 | 0.94 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8777010 | 0.91 | PRKCA (0.45) | ALDH1A1LMNAKDM4EPDE3APRKCA | |
| SCHEMBL8205815 | 0.89 | ALDH1A1 (0.38) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8777011 | 0.87 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL8777013 | 0.87 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL8777006 | 0.86 | KDM4E (0.35) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8777007 | 0.85 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8210030 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EHPGDADRA1A | |
| SCHEMBL8777016 | 0.82 | ALDH1A1 (0.37) | ALDH1A1LMNAKDM4EHPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693071-B1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0693071-A1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024134-A1 | NEW CARBOXYLIC-ACID ESTERS OF 2-AMINO-7-(1,3-DIHYDROXY-2-PROPOXYMETHYL)PURINE, THE PREPARATION OF SUCH ESTERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-27 | — | — | WO | disclosed |