Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.51 |
| ▸ | METAP1 | P53582 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763547 | 0.82 | METAP1 (0.51) | METAP2METAP1 | |
| SCHEMBL2991589 | 0.78 | NPC1 (0.56) | METAP2METAP1KDM4ENPC1RAB9A | |
| SCHEMBL369485 | 0.75 | METAP2 (0.61) | METAP2METAP1NPY5RADORA3KDM4E | |
| SCHEMBL20465968 | 0.74 | NPY5R (0.52) | METAP2METAP1NPY5REGFRPIK3CD | |
| SCHEMBL467132 | 0.74 | METAP2 (0.57) | METAP2METAP1NPY5REGFRADORA3 | |
| SCHEMBL183635 | 0.73 | METAP1 (0.56) | METAP2METAP1NPY5RPTGDR2 | |
| SCHEMBL2396563 | 0.71 | METAP2 (0.57) | METAP2METAP1NPY5RKDM4ENPC1 | |
| SCHEMBL10965168 | 0.71 | METAP2 (0.57) | METAP2METAP1NPY5RPIK3CDPIK3CA | |
| SCHEMBL302153 | 0.71 | EGFR (0.40) | EGFRPIK3CDPIK3CAKDM4ENPC1 | |
| SCHEMBL680854 | 0.71 | METAP2 (0.65) | METAP2METAP1NPY5RADORA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |