Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258906 | 0.89 | BPTF (0.50) | BPTFKAT2BALDH1A1DPP4PNMT | |
| SCHEMBL11019335 | 0.79 | CA12 (0.48) | ALDH1A1HPGDCXCL8APOBEC3GKDM4E | |
| SCHEMBL3293143 | 0.78 | CXCL8 (0.59) | BPTFKAT2BPNMTCXCL8RAB9A | |
| SCHEMBL2553273 | 0.77 | DPP4 (0.52) | DPP4PNMTAPOBEC3GKDM4ESMN1; SMN2 | |
| SCHEMBL29437737 | 0.77 | DPP4 (0.52) | DPP4PNMTAPOBEC3GKDM4ESMN1; SMN2 | |
| SCHEMBL1520973 | 0.77 | MAPT (0.56) | ALDH1A1HPGDCXCL8APOBEC3GKDM4E | |
| SCHEMBL11850186 | 0.77 | MAPT (0.54) | BPTFKAT2BALDH1A1HPGDDPP4 | |
| SCHEMBL28783831 | 0.76 | SIRT2 (0.53) | KDM4E | |
| SCHEMBL24728413 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDAPOBEC3GRAB9AGAA | |
| Hydrochloric Acid SCHEMBL8987512 | 0.75 | DPP4 (0.50) | DPP4PNMTAPOBEC3GKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800513-A1 | OPIATE RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5605932-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| US-5536868-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |
| WO-1996020921-A1 | OPIATE RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1996-07-11 | — | — | WO | disclosed |
| US-5481020-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |