Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420214 | 0.89 | MAPT (0.54) | ALOX5TRPM4MEN1KMT2AALDH1A1 | |
| SCHEMBL27809393 | 0.86 | GPR84 (0.42) | ALOX5MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30940211 | 0.85 | ERN1 (0.52) | ALOX5MEN1KMT2AMAPTNQO1 | |
| SCHEMBL30940210 | 0.85 | ERN1 (0.52) | ALOX5MEN1KMT2AMAPTNQO1 | |
| SCHEMBL16983223 | 0.84 | GPR84 (0.49) | ALOX5TRPM4NQO2MEN1KMT2A | |
| SCHEMBL21615614 | 0.81 | GPR84 (0.57) | ALOX5TRPM4NQO2MEN1KMT2A | |
| SCHEMBL22229791 | 0.81 | ME2 (0.52) | ALOX5TRPM4NQO2ALDH1A1KDM4E | |
| SCHEMBL16978927 | 0.80 | GPR84 (0.39) | ALOX5TRPM4NQO2MEN1KMT2A | |
| SCHEMBL15037543 | 0.80 | MAPT (0.44) | ALOX5NQO2MEN1KMT2AALDH1A1 | |
| SCHEMBL5727179 | 0.78 | MAPT (0.43) | ALOX5TRPM4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471498-B1 | Optical resolution method | KANKYO KAGAKU CENTER (JP) | 1997-12-17 | — | — | EP | claimed |
| EP-0471498-B1 | Optical resolution method | KANKYO KAGAKU CENTER (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5510520-A | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5395962-A | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0471498-A2 | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD (JP) | 1992-02-19 | — | — | EP | disclosed |