SCHEMBL8777450

SCHEMBL8777450

CCCCCC[C@@H](C)Oc1ccc(C(=O)Oc2ccc(C(=O)Oc3ccc4c(c3)CCC(C(=O)O[C@H](CCCCCC)C(F)(F)F)C4)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.38
ACHE P22303 6/20 0.34
TAOK3 Q9H2K8 2/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TAOK1 Q7L7X3 1/20 0.32
FAAH O00519 2/20 0.31
PNLIP P16233 1/20 0.31
PRSS1 P07477 1/20 0.31
ACR P10323 1/20 0.31
MAPT P10636 3/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777467 0.91 NPC1 (0.43) MCHR1ACHETAOK3NFKB1NFKB2
SCHEMBL8777445 0.90 NPC1 (0.41) MCHR1ACHETAOK3NFKB1NFKB2
SCHEMBL8579057 0.86 MCHR1 (0.41) MCHR1ACHETAOK3NFKB1NFKB2
SCHEMBL8777446 0.85 MCHR1 (0.34) MCHR1ACHETAOK3NFKB1NFKB2
SCHEMBL8777453 0.84 RARB (0.41) MCHR1SMN1; SMN2FAAHMAPT
SCHEMBL8997533 0.83 MCHR1 (0.40) MCHR1TAOK3NFKB1NFKB2RELA
SCHEMBL8536708 0.83 MCHR1 (0.50) MCHR1ACHETAOK3TAOK1FAAH
SCHEMBL8764270 0.81 NPC1 (0.44) MCHR1TAOK3NFKB1NFKB2RELA
SCHEMBL6936301 0.80 OPRK1 (0.38) ACHELMNAMAPTMEN1ALDH1A1
SCHEMBL8537183 0.80 OPRK1 (0.38) ACHELMNAMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549347-B1 Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements MITSUI PETROCHEMICAL IND (JP) 1997-10-29 EP disclosed
EP-0549347-A1 Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-06-30 EP disclosed