Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777445 | 0.91 | NPC1 (0.41) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8777467 | 0.90 | NPC1 (0.43) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8579057 | 0.88 | MCHR1 (0.41) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8777453 | 0.85 | RARB (0.41) | MCHR1SMN1; SMN2RARBMAPTFAAH | |
| SCHEMBL8777450 | 0.83 | MCHR1 (0.38) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8840209 | 0.82 | MCHR1 (0.47) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8531861 | 0.77 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8531556 | 0.77 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8536045 | 0.77 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8536706 | 0.77 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092258-A | — | — | None | — | — | JP | disclosed |
| JP-H0892258-A | TETRALIN COMPOUND AND LIQUID CRYSTAL ADDITIVE | MITSUI PETROCHEM IND LTD | 1996-04-09 | — | — | JP | disclosed |