SCHEMBL8777733

SCHEMBL8777733

CCCCN(CCCC)c1ccc(C(COCC(c2ccc(N(C)C)cc2)c2ccc(N(CCCC)CCCC)cc2C)c2ccc(N(C)C)cc2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.36
CNR2 P34972 1/20 0.35
MAPT P10636 3/20 0.34
HTT P42858 2/20 0.34
PKM P14618 1/20 0.34
MCL1 Q07820 1/20 0.34
CRHR1 P34998 3/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 4/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 4/20 0.32
MAPK1 P28482 3/20 0.32
SLC16A3 O15427 1/20 0.32
SLC16A1 P53985 1/20 0.32
LMNA P02545 3/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777674 0.96 GAA (0.35) GAACNR2MAPTHTTPKM
SCHEMBL8777774 0.90 S100B (0.38) GAACNR2MAPTHTTPKM
SCHEMBL8777606 0.87 S100B (0.42) GAAMAPTHTTPKMMCL1
SCHEMBL8777730 0.86 TDP1 (0.42) GAAMAPTHTTMEN1KMT2A
SCHEMBL8777692 0.86 MEN1 (0.35) GAACNR2MAPTMEN1KMT2A
SCHEMBL8777637 0.86 SLC2A1 (0.37) GAAMAPTCRHR1MEN1KMT2A
SCHEMBL8777681 0.82 GAA (0.37) GAACNR2MAPTHTTPKM
SCHEMBL8777564 0.82 SLC16A3 (0.36) GAACNR2MAPTMEN1KMT2A
SCHEMBL8777739 0.81 GAA (0.36) GAACNR2MAPTHTTPKM
SCHEMBL8777593 0.81 S100B (0.38) GAAMAPTHTTPKMMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed