SCHEMBL8777637

SCHEMBL8777637

Cc1cc(N(C)C)ccc1C(COCC(c1ccc(N(C)C)cc1)c1ccc(N(C)C)cc1C)c1ccc(N(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.37
ALDH1A1 P00352 8/20 0.36
GAA P10253 5/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 5/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
USP2 O75604 1/20 0.35
MAPK1 P28482 3/20 0.35
KDM4E B2RXH2 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
TSHR P16473 3/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CRHR1 P34998 1/20 0.33
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777606 0.90 S100B (0.42) SLC2A1ALDH1A1GAAL3MBTL1TDP1
SCHEMBL8777733 0.86 GAA (0.36) ALDH1A1GAATDP1MEN1KMT2A
SCHEMBL8777674 0.85 GAA (0.35) ALDH1A1GAATDP1MEN1KMT2A
SCHEMBL10349248 0.81 ALDH1A1 (0.48) SLC2A1ALDH1A1GAAL3MBTL1TDP1
SCHEMBL8777538 0.80 GAA (0.34) SLC2A1ALDH1A1GAAL3MBTL1TDP1
SCHEMBL8777593 0.77 S100B (0.38) ALDH1A1GAAL3MBTL1MAPTMAPK1
SCHEMBL5921994 0.76 SLC2A1 (0.47) SLC2A1ALDH1A1GAAL3MBTL1TDP1
SCHEMBL5009553 0.76 SLC2A1 (0.47) SLC2A1ALDH1A1GAAL3MBTL1TDP1
SCHEMBL10776452 0.76 MAPT (0.41) ALDH1A1GAAL3MBTL1TDP1MAPT
SCHEMBL8777673 0.76 SLC2A1 (0.40) SLC2A1ALDH1A1GAAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed