SCHEMBL8777748

SCHEMBL8777748

CCCCCCCCn1c(C)c(C(COCC(c2ccc(N(C)C)cc2)c2c(C)n(CCCCCCCC)c3ccccc23)c2ccc(N(C)C)cc2)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 0.42
CNR1 P21554 5/20 0.41
SLC6A3 Q01959 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
PSEN1 P49768 2/20 0.38
PSEN2 P49810 2/20 0.38
APH1B Q8WW43 2/20 0.38
NCSTN Q92542 2/20 0.38
APH1A Q96BI3 2/20 0.38
PSENEN Q9NZ42 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777784 0.87 CYP19A1 (0.42) KDM4EMAPTALDH1A1HTT
SCHEMBL8777753 0.85 CNR2 (0.42) CNR2CNR1SLC6A3KDM4EALDH1A1
SCHEMBL8777569 0.83 ALDH1A1 (0.45) KDM4EMAPTALDH1A1
SCHEMBL8777654 0.82 ALDH1A1 (0.42) KDM4EMAPTALDH1A1HTT
SCHEMBL8777581 0.78 MEN1 (0.41) CNR2CNR1SLC6A3MAPTALDH1A1
SCHEMBL8777611 0.77 ALDH1A1 (0.38) KDM4EMAPTALDH1A1HTT
SCHEMBL9657072 0.76 CNR2 (0.52) CNR2CNR1SLC6A3KDM4EMAPT
SCHEMBL10835401 0.74 CYP19A1 (0.39) CNR2KDM4EMAPTALDH1A1HTT
SCHEMBL10834697 0.74 ALDH1A1 (0.35) CNR2CNR1KDM4EMAPTALDH1A1
SCHEMBL8777643 0.73 ALDH1A1 (0.40) SLC6A3KDM4EMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed