SCHEMBL8777780

SCHEMBL8777780

CCCCCCCCOC(c1ccc(N(C)C)cc1)c1ccc(N(CC)CC)cc1OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 4/20 0.41
HNF4A P41235 1/20 0.41
CNR2 P34972 5/20 0.37
GAA P10253 1/20 0.36
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777688 1.00 RXRA (0.41) RXRAHNF4ACNR2GAAMEN1
SCHEMBL8777577 1.00 RXRA (0.41) RXRAHNF4ACNR2GAAMEN1
SCHEMBL8777701 0.92 RXRA (0.37) RXRAHNF4ACNR2GAAMEN1
SCHEMBL8777653 0.91 RXRA (0.38) RXRAHNF4AGAAMEN1KMT2A
SCHEMBL8777549 0.89 RXRA (0.37) RXRAHNF4AGAAMEN1KMT2A
SCHEMBL8777698 0.89 RXRA (0.37) RXRAHNF4AGAAMEN1KMT2A
SCHEMBL8777594 0.85 RXRA (0.40) RXRAHNF4ACNR2GAAMEN1
SCHEMBL8777708 0.84 CNR2 (0.32) RXRAHNF4ACNR2GAAMEN1
SCHEMBL8777629 0.83 ALDH1A1 (0.37) RXRAGAAMEN1KMT2APDE4A
SCHEMBL8777671 0.83 RXRA (0.37) RXRAHNF4ACNR2GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed