SCHEMBL8777833

SCHEMBL8777833

Nc1ccc([N+](=O)[O-])c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.66
MAPT P10636 3/20 0.66
APEX1 P27695 1/20 0.66
CASP6 P55212 1/20 0.66
ADORA2A P29274 4/20 0.66
CSNK1A1 P48729 2/20 0.66
CSNK1D P48730 2/20 0.66
CSNK1G1 Q9HCP0 2/20 0.66
MAOA P21397 2/20 0.66
FGR P09769 1/20 0.66
PIM1 P11309 1/20 0.66
DYRK1A Q13627 1/20 0.66
HIPK2 Q9H2X6 1/20 0.66
PTPRC P08575 4/20 0.57
S100A4 P26447 3/20 0.57
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HPGD P15428 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5109566 0.89 MAPT (0.79) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL10355816 0.87 TSHR (0.60) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL11250084 0.87 TSHR (0.60) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL11749574 0.87 TSHR (0.60) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL2205543 0.85 S100A4 (0.66) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL29400632 0.85 S100A4 (0.66) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL28785447 0.84 TDP1 (0.53) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL11759854 0.83 ALDH1A1 (0.71) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL28069586 0.82 TSHR (0.46) POLBMAPTAPEX1CASP6ADORA2A
SCHEMBL525762 0.81 ADORA2A (1.00) POLBMAPTADORA2ACSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119297188-A Preparation method of nanosheet-organic active molecule-catalyst hybrid material and application of nanosheet-organic active molecule-catalyst hybrid material in photoelectric storage integrated battery 中国科学院大连化学物理研究所 2025-01-10 CN claimed
EP-0103986-B1 ORGANIC ANTHRAQUINONE DYES CONTAINING SILANE GROUPS,PIGMENTS AND PROCESS FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-04-08 EP claimed
EP-0103986-A2 Organic anthraquinone dyes containing silane groups,pigments and process for preparing the same Montedison S.p.A. (IT) 1984-03-28 EP claimed
EP-0021264-B1 PROCESS FOR THE DELIGNIFICATION OF LIGNOCELLULOSIC MATERIALS BAYER AG (DE) 1983-01-19 EP claimed
US-4358392-A CONTAINING AN ANTHRAQUINONE HAVING AN AMINO GROUP AND HETEROCYCLIC SIDE CHAIN; MULTICOLOR; PHOTOCHROMISM ASULAB S.A. (CH) 1982-11-09 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-0021264-A1 Process for the delignification of lignocellulosic materials BAYER AG (DE) 1981-01-07 EP claimed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0337200-B1 Process for transferring dyes BASF AG (DE) 1995-06-07 EP disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0021264-A1 Process for the delignification of lignocellulosic materials BAYER AG (DE) 1981-01-07 EP disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
EP-0008063-A1 Azomethine derivatives of anthraquinones, methods for their preparation, their use in the pigmentation of organic macromolecular compounds and the materials thus obtained BAYER AG (DE) 1980-02-20 EP disclosed
US-4036838-A Process for the production of nitro derivatives of aromatic compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-4016182-A Process for the production of aminoanthraquinone compounds SANDOZ LTD. (CH) 1977-04-05 US disclosed