SCHEMBL8777879

SCHEMBL8777879

Nc1c(Cl)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.67
MAOB P27338 1/20 0.67
MEN1 O00255 7/20 0.62
KMT2A Q03164 7/20 0.62
ALDH1A1 P00352 6/20 0.62
MAPK1 P28482 5/20 0.62
MAPT P10636 5/20 0.62
POLB P06746 5/20 0.62
TDP1 Q9NUW8 4/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
THRB P10828 3/20 0.62
CYP3A4 P08684 3/20 0.62
MCL1 Q07820 3/20 0.62
LMNA P02545 2/20 0.62
TSHR P16473 2/20 0.62
CASP3 P42574 1/20 0.62
HBB P68871 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10733345 0.90 MEN1 (0.56) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL11850856 0.85 ADORA2A (0.61) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL10777248 0.84 S100A4 (0.52) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL30132359 0.81 MAOA (0.57) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL487001 0.80 MAOA (1.00) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL583089 0.80 ADORA2A (0.53) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL30129869 0.80 MAOA (1.00) MAOAMAOBMEN1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL6046897 0.78 MAOA (0.96) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL28865949 0.78 MEN1 (0.57) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL582033 0.77 CYP1A1 (0.72) MAOAMAOBMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4179450-A Process for the preparation of 1-acylamino-5(8)-chloroanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US claimed
CN-105694529-B Cationic reactive dye containing polyether amine chain segment and preparation method thereof 南京工业大学 2017-06-23 CN disclosed
CN-100408640-C Anthraquinone dyes CIBA SC HOLDING AG (CH) 2008-08-06 CN disclosed
CN-1796369-A Derivative of imide carbide in structure of quinone, preparation method and application UNIV ZHEJIANG POLYTECHNIC (CN) 2006-07-05 CN disclosed
CN-1643074-A Anthraquinone dyes CIBA SC HOLDING AG (CH) 2005-07-20 CN disclosed
CN-1349975-A Synthesis process of 1-amino-4-hydroxy anthraquinone derivative UNIV DALIAN SCIENCE & ENG (CN) 2002-05-22 CN disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
US-4179450-A Process for the preparation of 1-acylamino-5(8)-chloroanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4157893-A MONO OR DISAZO DYE CONTAINING AN AMINO-SUBSTITUTED PYRIMIDINE RING BASF AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-3972881-A VAT, CELLULOSE CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3935208-A NATURAL OR REGENERATED CELLULOSE ALTERMATT HANS 1976-01-27 US disclosed