Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 11/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876436 | 0.83 | SLC2A1 (0.35) | F10SLC2A1 | |
| SCHEMBL878283 | 0.79 | BDKRB1 (0.40) | BDKRB1F10 | |
| SCHEMBL876498 | 0.79 | SLC2A1 (0.38) | F10SLC2A1 | |
| SCHEMBL876778 | 0.78 | BDKRB1 (0.39) | BDKRB1F10CETP | |
| SCHEMBL878284 | 0.77 | F10 (0.39) | BDKRB1F10 | |
| SCHEMBL875679 | 0.77 | F10 (0.34) | F10SLC2A1 | |
| SCHEMBL785901 | 0.77 | BDKRB1 (0.47) | BDKRB1F10 | |
| SCHEMBL784683 | 0.74 | BDKRB1 (0.43) | BDKRB1F10CHRM4 | |
| SCHEMBL878326 | 0.73 | TLR9 (0.39) | F10 | |
| SCHEMBL784302 | 0.73 | BDKRB1 (0.43) | BDKRB1F10CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |