Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 15/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876437 | 0.84 | F10 (0.33) | F10 | |
| SCHEMBL878284 | 0.80 | F10 (0.39) | BDKRB1F10 | |
| SCHEMBL876499 | 0.80 | SLC2A1 (0.35) | F10 | |
| SCHEMBL877792 | 0.78 | BDKRB1 (0.40) | BDKRB1F10CETP | |
| SCHEMBL875680 | 0.78 | F10 (0.33) | F10 | |
| SCHEMBL878283 | 0.78 | BDKRB1 (0.40) | BDKRB1F10 | |
| SCHEMBL785901 | 0.75 | BDKRB1 (0.47) | BDKRB1F10 | |
| SCHEMBL878327 | 0.75 | TLR9 (0.36) | F10 | |
| SCHEMBL876160 | 0.72 | F10 (0.33) | F10 | |
| SCHEMBL784683 | 0.72 | BDKRB1 (0.43) | BDKRB1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |