Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873292 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL18787411 | 0.82 | KMT2A (0.67) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL10919578 | 0.80 | KMT2A (0.82) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL877171 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11349671 | 0.79 | MEN1 (0.76) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL764382 | 0.78 | KMT2A (0.62) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL379507 | 0.76 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL1845784 | 0.75 | KMT2A (0.70) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL18807161 | 0.75 | KMT2A (0.57) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL1842190 | 0.74 | GPR139 (0.54) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |