Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 14/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 14/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777776 | 0.84 | NPC1 (0.40) | SCN9ATLR8TLR7 | |
| SCHEMBL3787877 | 0.81 | CYP1A2 (0.39) | SCN9ATLR8TLR7LTA4H | |
| SCHEMBL13063428 | 0.81 | CYP1A2 (0.37) | SCN9A | |
| SCHEMBL3787471 | 0.81 | CYP1A2 (0.37) | TDP1 | |
| SCHEMBL8865272 | 0.81 | USP1 (0.39) | USP1WDR48 | |
| SCHEMBL13063655 | 0.81 | CYP1A2 (0.35) | — | |
| SCHEMBL8777811 | 0.81 | USP1 (0.44) | USP1WDR48LTA4H | |
| SCHEMBL8865669 | 0.80 | AR (0.36) | USP1WDR48TDP1TLR8TLR7 | |
| SCHEMBL3789630 | 0.80 | CYP1A2 (0.36) | SCN9A | |
| SCHEMBL8778052 | 0.80 | S1PR3 (0.37) | USP1WDR48SCN9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | USP1 2963/4885WDR48 4477/4885SCN9A 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.