Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.66 |
| ▸ | CTSS | P25774 | 6/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9787694 | 0.96 | CTSK (0.62) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7436235 | 0.88 | CTSS (0.70) | CTSKCTSSCA2ALDH1A1KDM4E | |
| SCHEMBL3721596 | 0.88 | CTSS (0.70) | CTSKCTSSCA2ALDH1A1KDM4E | |
| SCHEMBL10606387 | 0.88 | CTSS (0.70) | CTSKCTSSCA2ALDH1A1KDM4E | |
| SCHEMBL19115973 | 0.87 | CTSK (0.65) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19709962 | 0.86 | CYP1A2 (0.59) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9611898 | 0.86 | CTSS (0.74) | CTSKCTSSCA2ALDH1A1KDM4E | |
| SCHEMBL10606688 | 0.86 | CTSS (0.74) | CTSKCTSSCA2ALDH1A1KDM4E | |
| SCHEMBL19709746 | 0.85 | CYP1A2 (0.55) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| Iodide SCHEMBL7508332 | 0.85 | CTSS (0.66) | CTSKCTSSCA2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802923-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995035311-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |