Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766843 | 0.80 | ESR1 (0.51) | ESR1ESR2MAPTKMT2AGAA | |
| SCHEMBL10706661 | 0.78 | HSD17B10 (0.53) | ESR1ESR2MAPTKMT2AGAA | |
| SCHEMBL8767107 | 0.77 | ESR1 (0.48) | ESR1ESR2MAPTKMT2AGAA | |
| SCHEMBL8768074 | 0.77 | ESR1 (0.48) | ESR1ESR2MAPTKMT2AGAA | |
| SCHEMBL8768321 | 0.77 | ESR1 (0.48) | ESR1ESR2MAPTKMT2AGAA | |
| SCHEMBL8767056 | 0.75 | ESR1 (0.47) | ESR1ESR2ACMSDHNF4AMAPT | |
| SCHEMBL6264269 | 0.75 | HNF4A (0.53) | ESR1ESR2HNF4AMAPTKMT2A | |
| SCHEMBL9152464 | 0.75 | ACMSD (0.55) | ESR1ESR2ACMSDHNF4ADHFR | |
| SCHEMBL8768033 | 0.74 | ESR1 (0.46) | ESR1ESR2MCL1MAPTKMT2A | |
| SCHEMBL31090355 | 0.74 | AKR1C3 (0.48) | ACMSDHNF4ADHFRMCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585127-B1 | Thermal Recording sheet | JUJO PAPER CO LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5405821-A | Containing a 4-hydroxyphenylarylsulfone color developer | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |