Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778195 | 0.83 | FDPS (0.43) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9241339 | 0.76 | FDPS (0.49) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9244507 | 0.76 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9806687 | 0.76 | FDPS (0.49) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8778286 | 0.72 | FDPS (0.46) | FDPS | |
| SCHEMBL9084564 | 0.72 | FDPS (0.51) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8701605 | 0.71 | FDPS (0.51) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8706215 | 0.70 | FDPS (0.50) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8778247 | 0.68 | FDPS (0.33) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8778332 | 0.67 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648120-B1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMA (US) | 1997-12-29 | — | — | EP | claimed |
| EP-0648120-B1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMA (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1994000130-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |