Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778183 | 1.00 | ALOX5 (0.79) | ALOX5KCNH2PARP14PARP10DRD2 | |
| SCHEMBL8778188 | 1.00 | ALOX5 (0.79) | ALOX5KCNH2PARP14PARP10DRD2 | |
| SCHEMBL7971116 | 0.90 | ALOX5 (0.82) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL7971112 | 0.90 | ALOX5 (0.82) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL9163994 | 0.90 | ALOX5 (0.82) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL9158468 | 0.88 | ALOX5 (1.00) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL9158475 | 0.88 | ALOX5 (1.00) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL9163312 | 0.88 | ALOX5 (1.00) | ALOX5KCNH2PARP14PARP10 | |
| SCHEMBL9165813 | 0.85 | ALOX5 (0.74) | ALOX5KCNH2PARP14PARP10TNKS | |
| SCHEMBL9165807 | 0.85 | ALOX5 (0.74) | ALOX5KCNH2PARP14PARP10TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636119-B1 | PHENYL SUBSTITUTED CYCLOALKYL HYDROXYUREA DERIVATIVES WHICH INHIBIT LIPOXYGENASE | PFIZER (US) | 1997-11-05 | — | — | EP | disclosed |