Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 1.00 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158475 | 1.00 | ALOX5 (1.00) | ALOX5MMP13MAPTMEN1ALDH1A1 | |
| SCHEMBL9158468 | 1.00 | ALOX5 (1.00) | ALOX5MMP13MAPTMEN1ALDH1A1 | |
| SCHEMBL7971116 | 0.90 | ALOX5 (0.82) | ALOX5PARP10PARP14KCNH2 | |
| SCHEMBL7971112 | 0.90 | ALOX5 (0.82) | ALOX5PARP10PARP14KCNH2 | |
| SCHEMBL9163994 | 0.90 | ALOX5 (0.82) | ALOX5PARP10PARP14KCNH2 | |
| SCHEMBL9163641 | 0.88 | ALOX5 (0.79) | ALOX5MMP13MAPTMEN1ALDH1A1 | |
| SCHEMBL8778208 | 0.88 | ALOX5 (0.79) | ALOX5PARP10PARP14KCNH2 | |
| SCHEMBL8778183 | 0.88 | ALOX5 (0.79) | ALOX5PARP10PARP14KCNH2 | |
| SCHEMBL9163645 | 0.88 | ALOX5 (0.79) | ALOX5MMP13MAPTMEN1ALDH1A1 | |
| SCHEMBL8778188 | 0.88 | ALOX5 (0.79) | ALOX5PARP10PARP14KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558563-B1 | ANTI-INFLAMMATORY COMPOUNDS | WELLCOME FOUND (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1992009567-A1 | ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-11 | — | — | WO | claimed |
| EP-0558563-B1 | ANTI-INFLAMMATORY COMPOUNDS | WELLCOME FOUND (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1992009567-A1 | ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-11 | — | — | WO | disclosed |