Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.65 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061112 | 0.79 | FDPS (1.00) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL2459769 | 0.79 | FDPS (1.00) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL10621420 | 0.78 | FDPS (0.59) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL10001487 | 0.77 | FDPS (0.82) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL7863043 | 0.75 | FDPS (0.69) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL13991372 | 0.74 | FDPS (0.67) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL9546859 | 0.73 | FDPS (0.66) | FDPSBTN3A1PDE3ANAPRTTBXAS1 | |
| Phosphonic Acid SCHEMBL8733015 | 0.73 | FDPS (0.45) | FDPSBTN3A1PDE3A | |
| SCHEMBL8711897 | 0.73 | FDPS (0.65) | FDPSBTN3A1PDE3AKDM4ENAPRT | |
| SCHEMBL9547411 | 0.73 | FDPS (0.59) | FDPSKDM4ENAPRTTBXAS1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616560-A | Methods for the treatment of osteoporosis using bisphosphonates and parathyroid hormone | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-01 | — | — | US | claimed |
| EP-0648120-B1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMA (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5616560-A | Methods for the treatment of osteoporosis using bisphosphonates and parathyroid hormone | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0648120-A1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0618805-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS USING BISPHOSPHONATES AND PARATHYROID HORMONE | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994000129-A1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993011786-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS USING BISPHOSPHONATES AND PARATHYROID HORMONE | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-06-24 | — | — | WO | disclosed |