Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167703 | 0.81 | FDPS (0.42) | FDPSGRM8GRM4SMN1; SMN2LMNA | |
| SCHEMBL4443428 | 0.78 | FDPS (0.50) | FDPSGRM8GRM4SMN1; SMN2LMNA | |
| SCHEMBL5666093 | 0.75 | PGK1 (0.57) | FDPSGRM8GRM4SMN1; SMN2LMNA | |
| SCHEMBL6694239 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAL3MBTL1KCNN4KCNA5 | |
| Phosphonic Acid SCHEMBL8778216 | 0.73 | FDPS (0.65) | FDPSBTN3A1PDE3A | |
| SCHEMBL11061163 | 0.73 | SRC (0.56) | SMN1; SMN2LMNAL3MBTL1NPC1 | |
| SCHEMBL2461305 | 0.72 | SMN1; SMN2 (0.50) | FDPSGRM8GRM4SMN1; SMN2LMNA | |
| SCHEMBL15263677 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAL3MBTL1KCNN4KCNA5 | |
| SCHEMBL1472577 | 0.71 | SMN1; SMN2 (0.49) | FDPSGRM8GRM4SMN1; SMN2LMNA | |
| SCHEMBL4611699 | 0.71 | SMN1; SMN2 (0.49) | FDPSGRM8GRM4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779813-A4 | PHOSPHONATES AND PARATHYROID HORMONE FOR OSTEOPOROSIS | PROCTER & GAMBLE (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0779812-A4 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS USING BONE ACTIVE PHOSPHONATES AND PARATHYROID HORMONE | PROCTER & GAMBLE (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0779813-A1 | PHOSPHONATES AND PARATHYROID HORMONE FOR OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0779812-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS USING BONE ACTIVE PHOSPHONATES AND PARATHYROID HORMONE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| WO-1996007418-A1 | PHOSPHONATES AND PARATHYROID HORMONE FOR OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1996007417-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS USING BONE ACTIVE PHOSPHONATES AND PARATHYROID HORMONE | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |