Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8468445 | 0.98 | FDPS (0.34) | FDPSCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8385047 | 0.83 | FDPS (0.42) | FDPSCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8778371 | 0.82 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4METAP1 | |
| Iodide SCHEMBL8384545 | 0.82 | FDPS (0.41) | FDPSCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL8467473 | 0.82 | FDPS (0.41) | FDPSCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8778259 | 0.81 | FDPS (0.38) | FDPSSMPD1 | |
| Hydrochloric Acid SCHEMBL8468414 | 0.81 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL8467287 | 0.80 | FDPS (0.37) | FDPSSMPD1 | |
| SCHEMBL8778434 | 0.76 | FDPS (0.34) | FDPSSMPD1 | |
| Iodide SCHEMBL7860080 | 0.76 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648120-B1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMA (US) | 1997-12-29 | — | — | EP | claimed |
| EP-0648120-A1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-04-19 | — | — | EP | claimed |
| WO-1994000129-A1 | USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | claimed |