SCHEMBL8778326

SCHEMBL8778326

Oc1ccc(O)c(OC(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.54
APP P05067 12/20 0.50
KCNH2 Q12809 3/20 0.40
TMEM97 Q5BJF2 3/20 0.40
SIGMAR1 Q99720 3/20 0.40
NR1I2 O75469 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
MIF P14174 1/20 0.39
TYR P14679 1/20 0.39
ALOX15 P16050 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HSD17B10 Q99714 1/20 0.39
P2RX1 P51575 1/20 0.37
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3026638 0.84 EPHX2 (0.41) MAOBAPPEPHX2
SCHEMBL3812590 0.84 ALOX5 (0.50) APP
SCHEMBL23484366 0.83 EPHX2 (0.40) MAOBAPPNR1I2ALDH1A1LMNA
SCHEMBL14121378 0.81 APP (0.49) APPKCNH2TMEM97SIGMAR1P2RX1
SCHEMBL29890447 0.81 EPHX2 (0.42) MAOBAPPKCNH2TMEM97SIGMAR1
SCHEMBL2097133 0.81 APP (0.49) APPKCNH2TMEM97SIGMAR1HTT
SCHEMBL4055218 0.81 EPHX2 (0.42) MAOBAPPKCNH2TMEM97SIGMAR1
SCHEMBL4849499 0.81 APP (0.49) APPKCNH2TMEM97SIGMAR1ALDH1A1
SCHEMBL1978168 0.79 MAOB (0.36) MAOBAPPALDH1A1LMNAALOX15
SCHEMBL363418 0.79 HSD17B10 (0.46) MAOBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed
EP-0813560-A2 SOLUBLE FLUORINATED POLY-P-PHENYLENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-29 EP disclosed
WO-1996028491-A1 SOLUBLE FLUORINATED POLY-P-PHENYLENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-19 WO disclosed