Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | GCLC | P48506 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KYNU | Q16719 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24485485 | 1.00 | NOS2 (0.39) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL17613156 | 0.80 | PMP22 (0.54) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL7873430 | 0.80 | PMP22 (0.54) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL4437685 | 0.80 | PMP22 (0.54) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL15946195 | 0.80 | NOS2 (0.39) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL5842241 | 0.78 | PMP22 (0.47) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL19222940 | 0.78 | GCLC (0.44) | NOS2PMP22GCLCSLC1A3SLC1A2 | |
| SCHEMBL5717764 | 0.78 | PMP22 (0.47) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL618202 | 0.77 | SLC22A6 (0.37) | NOS2PMP22GCLCALOX15BLM | |
| SCHEMBL618201 | 0.77 | SLC22A6 (0.37) | NOS2PMP22GCLCALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745283-A | Heterocyclic derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-12 | — | — | CN | disclosed |
| EP-0813542-A1 | AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |