Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | KYNU | Q16719 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873430 | 1.00 | PMP22 (0.54) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL17613156 | 1.00 | PMP22 (0.54) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL18782794 | 0.82 | PMP22 (0.50) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL18782774 | 0.82 | PMP22 (0.50) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL18782571 | 0.82 | PMP22 (0.50) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL20739371 | 0.81 | PMP22 (0.50) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL8736543 | 0.81 | PMP22 (0.67) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL24485485 | 0.80 | NOS2 (0.39) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL15946195 | 0.80 | NOS2 (0.39) | PMP22NOS2KYNUSLC1A3SLC1A2 | |
| SCHEMBL8778376 | 0.80 | NOS2 (0.39) | PMP22NOS2KYNUSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | claimed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | claimed |
| US-5541290-A | OLIGOPEPTIDE CONTAINING ALPHA-KETOAMIDE GROUP, TREATMENT OF ALZHEIMER*S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS | CORTEX PHARMACEUTICALS, INC. | 1996-07-30 | — | — | US | claimed |
| WO-1995000535-A1 | OPTICALLY PURE CALPAIN INHIBITOR COMPOUNDS | ALKERMES, INCORPORATED (US) | 1995-01-05 | — | — | WO | claimed |
| EP-4734770-A1 | COMPOUNDS THAT MODULATE GPRC6A RECEPTOR AND PET FOOD PRODUCTS CONTAINING THE SAME | Mars, Incorporated (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006362-A1 | COMPOUNDS THAT MODULATE GPRC6A RECEPTOR AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2025-01-02 | — | — | WO | disclosed |
| US-11149066-B2 | Thrombospondin 1-binding peptide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11008287-B2 | Sulfoxyalkyl organonitro and related compounds and pharmaceutical compounds for use in medicine | EPICENTRX, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-10668175-B2 | Cathepsin-binding compounds bound to a carrier and their diagnostic use | J. STEFAN INSTITUTE (SI) | 2020-06-02 | — | — | US | disclosed |
| US-20200157047-A1 | SULFOXYALKYL ORGANONITRO AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOUNDS FOR USE IN MEDICINE | EPICENTRX, INC. | 2020-05-21 | — | — | US | disclosed |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-04-30 | — | — | US | disclosed |
| WO-2018071741-A1 | SULFOXYALKYL ORGANONITRO AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN MEDICINE | EPICENTRIX, INC. (US) | 2018-04-19 | — | — | WO | disclosed |
| US-5658939-A | PREVENTION THROMBOSIS IN MAMMALS | CORVAS INTERNATIONAL INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5646165-A | ANTITHROMBOTIC AGENTS | CORVAS INTERNATIONAL, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0765340-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5541290-A | OLIGOPEPTIDE CONTAINING ALPHA-KETOAMIDE GROUP, TREATMENT OF ALZHEIMER*S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS | CORTEX PHARMACEUTICALS, INC. | 1996-07-30 | — | — | US | disclosed |
| WO-1995028420-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-10-26 | — | — | WO | disclosed |
| WO-1995000535-A1 | OPTICALLY PURE CALPAIN INHIBITOR COMPOUNDS | ALKERMES, INCORPORATED (US) | 1995-01-05 | — | — | WO | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4247543-A | OLIGOPEPTIDES; ANALGESICS; NERVOUS SYSTEM DISORDERS | SANDOZ LTD. (CH) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10668175-B2 | Cathepsin-binding compounds bound to a carrier and their diagnostic use | CTSB, CTSV, CTSE | PMP22 1626/4885NOS2 3870/4885KYNU 2892/4885 |
| US-11149066-B2 | Thrombospondin 1-binding peptide | SERPINC1, TEK, ARGLU1 | PMP22 2282/4885NOS2 1755/4885KYNU 2137/4885 |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | SERPINC1, TEK, ARGLU1 | PMP22 2282/4885NOS2 1755/4885KYNU 2137/4885 |
| US-11008287-B2 | Sulfoxyalkyl organonitro and related compounds and pharmaceutical compounds for use in medicine | AS3MT, SLC10A6, SLCO1B3 | PMP22 30/4885NOS2 2640/4885KYNU 52/4885 |
| US-20200157047-A1 | SULFOXYALKYL ORGANONITRO AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOUNDS FOR USE IN MEDICINE | AS3MT, SLC10A6, SLCO1B3 | PMP22 30/4885NOS2 2640/4885KYNU 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.