Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21388518 | 0.90 | PLA2G2A (0.56) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL17835021 | 0.88 | PLA2G2A (0.59) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL12550198 | 0.88 | PLA2G2A (0.59) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL6462571 | 0.86 | TP53 (0.53) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL8778527 | 0.85 | AHR (0.50) | PLA2G2ABLMNR5A1TSHRLTA4H | |
| SCHEMBL8728856 | 0.84 | TP53 (0.51) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL1070543 | 0.84 | TP53 (0.56) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL14331832 | 0.84 | PLA2G2A (0.48) | PLA2G2ABLMTP53ALOX15NR5A1 | |
| SCHEMBL11038649 | 0.82 | TP53 (0.54) | PLA2G2ATP53ALOX15TSHRALDH1A1 | |
| SCHEMBL8956013 | 0.81 | TP53 (0.54) | PLA2G2ABLMTP53ALOX15NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |