Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 11/20 | 0.45 |
| ▸ | CNR2 | P34972 | 11/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848719 | 0.90 | AHR (0.58) | AHRPLA2G2ACNR1CNR2BLM | |
| SCHEMBL28360552 | 0.88 | PLA2G2A (0.59) | AHRPLA2G2ACNR1CNR2BLM | |
| SCHEMBL8778636 | 0.86 | ALDH1A1 (0.46) | AHRPLA2G2ACNR1CNR2TSHR | |
| SCHEMBL8778517 | 0.85 | PLA2G2A (0.49) | PLA2G2ACNR1CNR2BLMNR5A1 | |
| SCHEMBL23457915 | 0.84 | AHR (0.65) | AHRPLA2G2ACNR1CNR2NR5A1 | |
| SCHEMBL26976511 | 0.84 | AHR (0.65) | AHRPLA2G2ACNR1CNR2NR5A1 | |
| SCHEMBL8956129 | 0.81 | CNR2 (0.53) | AHRPLA2G2ACNR1CNR2BLM | |
| SCHEMBL8778627 | 0.81 | TSHR (0.62) | TSHRLTA4H | |
| SCHEMBL8778575 | 0.81 | PLA2G2A (0.49) | PLA2G2ABLMNR5A1TSHRALDH1A1 | |
| SCHEMBL5269400 | 0.80 | CNR1 (0.49) | PLA2G2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |