Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044621 | 0.94 | MAOB (0.47) | MAOBAOC3EPHX2MRGPRX4FFAR1 | |
| SCHEMBL1044641 | 0.89 | EPHX2 (0.47) | HDAC1HDAC2MAOBAOC3EPHX2 | |
| SCHEMBL8778594 | 0.88 | TSHR (0.42) | HDAC1HDAC2LTA4HCHRM5EPHX2 | |
| SCHEMBL1046561 | 0.87 | EPHX2 (0.46) | HDAC1HDAC2MAOBAOC3EPHX2 | |
| SCHEMBL8778595 | 0.87 | EPHX2 (0.46) | HDAC1HDAC2MAOBAOC3EPHX2 | |
| SCHEMBL8778597 | 0.87 | EPHX2 (0.46) | HDAC1HDAC2MAOBAOC3EPHX2 | |
| SCHEMBL1045849 | 0.85 | MAOB (0.45) | MAOBAOC3CHRM5EPHX2MRGPRX4 | |
| SCHEMBL5535120 | 0.81 | EPHX2 (0.47) | LTA4HEPHX2MMP2MMP9MMP14 | |
| SCHEMBL8955539 | 0.81 | HDAC1 (0.50) | HDAC1HDAC2MAOBAOC3LTA4H | |
| SCHEMBL5542307 | 0.78 | LTA4H (0.45) | LTA4HEPHX2MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |