Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778597 | 1.00 | EPHX2 (0.46) | EPHX2MRGPRX4HDAC1HDAC2HDAC3 | |
| SCHEMBL1046561 | 1.00 | EPHX2 (0.46) | EPHX2MRGPRX4HDAC1HDAC2HDAC3 | |
| SCHEMBL1044641 | 0.98 | EPHX2 (0.47) | EPHX2MRGPRX4HDAC1HDAC2HDAC3 | |
| SCHEMBL1044621 | 0.92 | MAOB (0.47) | EPHX2MRGPRX4MAOBAOC3FFAR1 | |
| SCHEMBL8778522 | 0.87 | HDAC1 (0.44) | EPHX2MRGPRX4HDAC1HDAC2MAOB | |
| SCHEMBL1045849 | 0.86 | MAOB (0.45) | EPHX2MRGPRX4MAOBAOC3FFAR1 | |
| SCHEMBL8778525 | 0.83 | HDAC1 (0.45) | MRGPRX4HDAC1HDAC2 | |
| SCHEMBL2090926 | 0.81 | HDAC1 (0.46) | EPHX2MRGPRX4HDAC1HDAC2HDAC3 | |
| SCHEMBL1046516 | 0.81 | NOS1 (0.52) | MRGPRX4MAOBAOC3PPARA | |
| SCHEMBL13724108 | 0.81 | EPHX2 (0.46) | EPHX2MRGPRX4HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |