Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043999 | 1.00 | HRH3 (0.53) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL8778548 | 1.00 | HRH3 (0.53) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL8778546 | 1.00 | HRH3 (0.53) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL8778507 | 1.00 | HRH3 (0.53) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL1045733 | 0.98 | ALDH3A1 (0.53) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL1077698 | 0.91 | DRD4 (0.52) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL11815991 | 0.89 | HRH3 (0.61) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL30514014 | 0.89 | HRH3 (0.61) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL9770302 | 0.87 | ALDH3A1 (0.62) | HRH3ALDH3A1DRD4DRD2DRD3 | |
| SCHEMBL712373 | 0.85 | DRD4 (0.48) | HRH3ALDH3A1DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |