Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 4/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626503 | 0.93 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL26313182 | 0.93 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL5481104 | 0.93 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31271719 | 0.93 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28723570 | 0.93 | LMNA (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28328035 | 0.93 | LMNA (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28581774 | 0.93 | LMNA (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27699391 | 0.93 | LMNA (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8108622 | 0.91 | LMNA (0.48) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Dodecanol SCHEMBL9777570 | 0.91 | LMNA (0.61) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |
| CN-1086217-A | The derivative of Phosphinyloxy propanaminium inner salt | SANDOZ LTD (CH) | 1994-05-04 | — | — | CN | disclosed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | disclosed |