Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21633733 | 0.98 | HRH3 (0.54) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL11360661 | 0.92 | HRH3 (0.54) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL22248703 | 0.90 | HRH3 (0.65) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL22248702 | 0.88 | HRH3 (0.62) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL214703 | 0.86 | KDM4E (0.54) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL20234326 | 0.84 | HRH3 (0.61) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL23266158 | 0.83 | NR5A1 (0.61) | HRH3KDM4ERAB9ANPC1LMNA | |
| SCHEMBL12372939 | 0.83 | HRH3 (0.58) | HRH3KDM4EMEN1KMT2APOLB | |
| SCHEMBL12762363 | 0.83 | NR5A1 (0.61) | HRH3KDM4ERAB9ANPC1LMNA | |
| SCHEMBL13216578 | 0.83 | NR5A1 (0.61) | HRH3KDM4ERAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |