Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939116 | 1.00 | FAAH (0.41) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL6938620 | 0.94 | DNM1 (0.41) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL9934670 | 0.92 | EPHX2 (0.37) | FAAHDNM1OPRM1EPHX2 | |
| SCHEMBL14693795 | 0.90 | FAAH (0.42) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL9408548 | 0.90 | DNM1 (0.39) | FAAHDNM1OPRM1CNR1CNR2 | |
| Ethylene SCHEMBL10617839 | 0.88 | DNM1 (0.45) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL5101333 | 0.88 | EPHX2 (0.34) | FAAHDNM1OPRM1EPHX2 | |
| SCHEMBL3039218 | 0.87 | DNM1 (0.48) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL4022359 | 0.87 | DNM1 (0.48) | FAAHDNM1OPRM1CNR1CNR2 | |
| SCHEMBL7082641 | 0.87 | DNM1 (0.48) | FAAHDNM1OPRM1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |