Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039560 | 0.89 | MRGPRX4 (0.48) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL10778567 | 0.83 | S1PR1 (0.50) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL16224816 | 0.83 | S1PR1 (0.50) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL8955969 | 0.83 | ALDH1A1 (0.52) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL29919692 | 0.83 | S1PR1 (0.50) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL16859321 | 0.83 | S1PR1 (0.50) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL5888832 | 0.81 | MRGPRX4 (0.48) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL31706008 | 0.81 | MRGPRX4 (0.48) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL31267610 | 0.80 | MRGPRX4 (0.42) | MRGPRX4RXRARXRBRXRGMCL1 | |
| SCHEMBL535975 | 0.80 | RXRA (0.49) | MRGPRX4RXRARXRBRXRGMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |