⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL4788802 | 0.91 | ODC1 (0.32) | — | |
| SCHEMBL31469075 | 0.79 | — | — | |
| Ethylenediamine SCHEMBL5185534 | 0.78 | DNM1 (0.42) | — | |
| SCHEMBL7921744 | 0.73 | — | — | |
| SCHEMBL11026624 | 0.71 | — | — | |
| Butane SCHEMBL10702549 | 0.69 | CYP3A4 (0.40) | — | |
| SCHEMBL258983 | 0.69 | — | — | |
| SCHEMBL191489 | 0.69 | — | — | |
| SCHEMBL681190 | 0.69 | — | — | |
| Ethylene SCHEMBL248596 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039326-C | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD (CH) | 1998-07-29 | — | — | CN | disclosed |
| CN-1039326-C | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD (CH) | 1998-07-29 | — | — | CN | disclosed |
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |
| CN-1086217-A | The derivative of Phosphinyloxy propanaminium inner salt | SANDOZ LTD (CH) | 1994-05-04 | — | — | CN | disclosed |
| CN-1086217-A | The derivative of Phosphinyloxy propanaminium inner salt | SANDOZ LTD (CH) | 1994-05-04 | — | — | CN | disclosed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | disclosed |