Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690577 | 0.91 | KAT6A (0.42) | F10F2PRSS1KAT6AGCK | |
| SCHEMBL8778662 | 0.85 | MEN1 (0.37) | F10GCKABL1 | |
| SCHEMBL8499411 | 0.85 | GCK (0.42) | F10GCK | |
| SCHEMBL8068683 | 0.85 | SMN1; SMN2 (0.41) | F10GCK | |
| SCHEMBL8831794 | 0.84 | PDE4A (0.41) | GCKADORA3 | |
| Hydrochloric Acid SCHEMBL8743784 | 0.84 | GCK (0.42) | F10GCK | |
| Hydrochloric Acid SCHEMBL8059609 | 0.84 | SMN1; SMN2 (0.40) | F10GCK | |
| Hydrochloric Acid SCHEMBL8070337 | 0.83 | MAPT (0.38) | MAPK14 | |
| SCHEMBL8831819 | 0.83 | MEN1 (0.40) | GCK | |
| SCHEMBL8778655 | 0.83 | SLC9A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640593-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0640593-A1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |